2-(3-isopropoxyphenyl)propanoic acid - Names and Identifiers
2-(3-isopropoxyphenyl)propanoic acid - Introduction
2-(3-isopropoxyphenyl)propanoic acid is an organic compound commonly abbreviated as IPPBA. The following is a description of its nature, use, preparation and safety information:
1. Nature:
-Appearance: Colorless or light yellow crystal
-molecular formula: C12H16O3
-Molecular weight: 208.25g/mol
-Melting point: 82-84 degrees Celsius
-Boiling point: 375 degrees Celsius
-Soluble: Soluble in ethanol, acetone and dichloromethane
2. Use:
-Pharmaceutical field: IPPBA is widely used as an intermediate and active ingredient of non-steroidal anti-inflammatory drugs (NSAIDs) in medicine, and has anti-inflammatory and analgesic effects.
-Cosmetics: IPPBA can be used in anti-aging, soothing and protecting skin care products.
-Other fields: IPPBA can also be used for the preparation of synthetic organic compounds and pesticide intermediates.
3. Preparation method:
IPPBA can be synthesized by the following steps:
-Step 1: React 2-bromoacetophenone with 3-isopropoxybenzene to generate 2-(3-isopropoxyphenyl) ethanone.
-Step 2: 2-(3-isopropoxyphenyl) ethanone is reacted with sodium cyanide in acetonitrile to generate 2-(3-isopropoxyphenyl) acetone.
-Step 3: React 2-(3-isopropoxyphenyl) acetone with sodium borohydride in ethanol to produce the target product 2-(3-isopropoxyphenyl)propanoic acid.
4. Safety Information:
-Wear appropriate chemical protective gloves and goggles when preparing and using IPPBA. Avoid contact with skin and eyes.
-Pay attention to the fire source and electrostatic discharge during operation and storage to prevent spontaneous combustion or explosion.
- IPPBA is an organic compound and should be kept away from fire and high temperature environments.
-During storage, IPPBA should be sealed and stored in a cool, dry and well-ventilated place.
Last Update:2024-04-09 02:00:52